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Isoflavones and flavonols, two types of flavenoids known for their antioxidant properties, have been shown to reduce ovarian cancer risk, according to a study by Dr. Maria Rossi of the Ricerche Farmacologiche “Mario Negre” in Milan, published in the International Journal of Cancer.
In a study of 1,031 women diagnosed with epithelial ovarian cancer and 2,411 women who had been hospitalized for non-cancer related conditions, adjusting for other factors such as birth control pill use and family cancer history, it was found that a high intake of isoflavones cut ovarian cancer risk by 49 percent.
Women with the highest flavenol intake were 37 percent less likely to have ovarian cancer than women with the lowest flavenol intake.
Other flavenoids showed no difference from the control group.
Isoflavones are found in tea and soy, and flavenols are found in cocoa, and other fruits and vegetables. Having chocolate with ones tea is probably a good idea.
In July 2006 the FDA approved Merck’s Gardisil for sale and marketing to girls and women ages nine to 26. Gardisal was shown to be 100% effective in preventing infection by strains 16 and 18 of HPV, the human papillomavirus which causes about 70% of cervical cancer cases.
Merck, with support by the CDC, quickly began lobbying state legislatures to pass laws mandating that middle school age girls receive the vaccine. In 2007 Merck backed off their lobbying efforts.
In Australia, where 3.7 million doses of the vaccine have already been distributed, about 1,013 adverse reactions have been reported including soreness, swelling, redness or other reaction at the injection site, dizzines, neusea, vomiting, and a possibility of pancreatitis. Three women developed pancreatitis soon after inoculation.
Pancreatitis is a sudden attack of severe upper abdominal pain where pancreatic enzymes irritate and burn the pancreas, and leak out into the abdominal cavity, which can result in serious complications including respiratory, kidney or heart failure, all potentially fatal.
The claims linking Gardasil to pancreatitis, published in The Medical Journal of Australia, were made by Dr. Amitabha Das and his colleagues who say an extensive investigation could find no other cause for the pancreatitis and while a coincidental illness could not be ruled out, “neither can HPV vaccination be excluded as a potential cause”.
The Theraputic Goods Administration (TGA), the Australian regulatory body is investigating the claims.
The UK government Department of Health has mandated that all schoolgirls aged 12 through 13 be routinely vaccinated against the HPV virus, but have chosen Glaxo-Kline’s Cervarex over Merck’s Gardasil. They cite cost as the deciding factor.
This blog deals with cancer and would not normally discuss cardiovascular disease, but today’s entry has to touch on both as the reduction of LDL cholesterol, one of the goals of many physicians for preventing cardiovascular disease, causes increased cancer risk.
Most people, including many physicians, do not understand the mechanics of heart disease. A study of the works of Linus Pauling and Louis Ignarro, both Nobel prize winners for their research on cardiovascular disease, gives a glimpse into how cardiovascular disease occurs.
Linus Pauling found that the triple helix of collagen, which supports all of the blood vessels in the body giving them their elasticity and their strength, breaks down, allowing the vessels, particularly near the heart where the pressure is greatest, to begin to shred and form cracks.
Cholesterol in the blood senses there is a break in the vessel wall and patches it, much in the same way blood forms a scab on a wound.
As this cholesterol builds up on the break in the vessel wall, it causes turbulence which, in turn, creates blood clots. These cause strokes and heart attacks.
More recently, Louis Ignarro of the UCLA Department of Pharmacology, discovered that nitric oxide produced by the vessels walls is the key to keeping the vessels open and flexible. As we age the vessels lose this ability to produce nitric oxide.
Nitric oxide cannot be added externally as it only exists for a very short period of time. It can only be produced in the body by the blood vessel walls themselves.
Supplementing the diet with L-Arginine and L-Citrulline causes an increase in nitric oxide. This not only keeps the blood vessels healthy, but actually reduces plaque which is a build up of cholesterol and other components in the blood.
What has this to do with cancer?
In a study led by Dr. Richard Karas of the Tufts Medical Center in Boston to determine if statin drugs, which are used to reduce LDL cholesterol in the blood, cause cancer, it was found that those persons with the lowest LDL cholesterol had a four-fold increase in the incidence of cancer over those with the highest LDL cholesterol.
It would appear that the medical and pharmaceutical community, by urging patients to lower their cholesterol with statin drugs rather than increasing the production of nitric oxide by taking l-Arginine and L-Citrulline are actually causing cancer!
Information found on this site has been culled from articles dealing with cancer and its treatment. I research the information back to the abstracts or papers from which it originates, usually written by doctors at a university or other research facility. It is my intent to disseminate as much information as widely as is possible. My interest in cancer comes from losing several family members, including my wife, to the disease and its subsequent treatment. I hope that the information provided proves to be of some value to those reading it.
Isoflavones and flavonols, two types of flavenoids known for their antioxidant properties, have been shown to reduce ovarian cancer risk, according to a study by Dr. Maria Rossi of the Ricerche Farmacologiche “Mario Negre” in Milan, published in the International Journal of Cancer.
